Inducible RNA Interference of brlAb in Aspergillus nidulans





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Barton LM, Prade RA 2008 Inducible RNA Interference of brlAb in Aspergillus nidulans. Eukaryotic Cell 7:2004-2007

An inducible RNA interference (RNAi) construct composed of inverted repeating alcA promoters flanking the developmental regulatory gene brlA was tested in Aspergillus nidulans. On inducing medium, the RNAi strains failed to sporulate and lacked brlA and brlA expression. RNAi was specific for brlAa, but not brlAb, silencing, indicating brlAa regulation by brlAb.



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